Stworzyć plik /etc/udev/rules.d/01-touchpad.rules

Zawartość:

SUBSYSTEM=="usb", SYSFS{product}=="\*Mouse\*"

ACTION=="add", SUBSYSTEM=="input", ENV{ID\_CLASS}="mouse",
RUN+="/usr/bin/synclient TouchpadOff=1"

ACTION=="remove", SUBSYSTEM=="input", ENV{ID\_CLASS}="mouse",
RUN+="/usr/bin/synclient TouchpadOff=0"